一.下面由东康源为您对雷帕霉素原料药做一番简单的介绍：

1.cas 登入号：53123-88-9

2.产品分子式：C51H79NO13 

3.产品分子量：914.18

4.外观和性状：为白色固体结晶，熔点为183-185℃，亲脂性，溶解于甲醇、乙醇、丙酮、氯仿等有机溶剂，极微溶于水，几乎不溶于乙醚

5.作用及用途：雷帕霉素是一种疗效好，低毒，无肾毒性的新型免疫抑制剂。

新用途

美国德克萨斯州大学最新研究显示，雷帕霉素可用于治疗阿尔茨海默症，该药物成分也存在于复活岛土壤中细菌的分泌物。

2010年3月，据国外媒体报道，科学家近期最新发现它另外一种用途：可用于治疗阿尔茨海默症（老年性痴呆）。

Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. It prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2).

A macrolide, sirolimus was discovered by Brazilian researchers as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island[1] - an island also known as Rapa Nui.[2] It was approved by the FDA in September 1999 and is marketed under the trade name Rapamune by Pfizer (formerly by Wyeth).

Sirolimus was originally developed as an antifungal agent. However, this use was abandoned when it was discovered to have potent immunosuppressive and antiproliferative properties. It has since been shown to prolong the life of mice and might also be useful in the treatment of certain cancers.

Technical Data

M.Wt:914.18Formula:C51H79NO13Solubility:Soluble to 100 mM in ethanol and to 50 mM in DMSOPurity:>98 %Storage:Desiccate at -20°CCAS No:53123-88-9The technical data provided above is for guidance only.

For batch specific data refer to the Certificate of Analysis.

二.如果还想详细了解雷帕霉素原料药的话，不妨看看下面的参数：

1.中文名称：雷帕霉素

2.中文别名：西罗莫司

3.化学名称：雷帕霉素原料药

4.英文名称：rapamycin

    

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