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胶原蛋白II型/Collagen Type II/来源于牛鼻膜/SIGMA C7806,100%产品编号：C01670中文名称：胶原蛋白II型/Collagen Type II/来源于牛鼻膜/SIGMA C7806英文名称：Collagen Type IICAS号:9007-34-5纯度:100�号:232-697-4MDL号:MFCD00130825

订货信息：产品规格价格(RMB)C01670-5MG800C01670-10MG1400

性能描述

性状	白色冻干粉
溶解性	aqueous acid: soluble
保存温度	2-8 C

Preparation Note
An acid soluble collagen soluble in dilute acetic acid at pH 3.0 (5 mg/ml), yielding an opalescent, colorless solution.

Collagen Type II is a triple helix composed of three 1(II) strands.

Application
Collagen-type II has been investigated for its importance in haemostasis. Two peptides, CB8 and CB11, are sites of platelet binding and activation on collagen-type 2. Collagen-type 2 has also been used as a model for arthritis in animals, where FR140423, a selective cyclooxygenase (COX)-2 inhibitor, has shown an anti-inflammatory effect without gastric lesions that may occur with treatment via indomethacin.
Collagen Type II is sometimes used to induce an animal model of rheumatoid arthritis. However, under conditions leading to formation of reactive oxygen species, the subjects develop tolerance for auto-antibodies. This is an unusual situation of ROS having a favorable effect.

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